BIOTER S.A. pursuant to Law 3556/2007 announces 1) the shareholder Mr.George Mavroskotis General Manager and Managing Director of BIOTER SA, person obligated to notify pursuant to Law 3340/2005, on 06/01/2010 purchased 130,000 BIOTER's common registered shares of total value of Euro 20,677.92 2) the shareholder Mrs. Antonia Katsarou, person obligated to notify pursuant to Law 3340/2005, on 06/01/2010 sold 213,508 BIOTER's common registered shares of total value of Euro 34,161.28