BIOTER S.A.

Announcement of Regulated Information according to Law 3556/2007

BIOTER S.A. pursuant to Law 3556/2007 announces 1) the shareholder Mr.George Mavroskotis General Manager and Managing Director of BIOTER SA, person obligated to notify pursuant to Law 3340/2005, on 06/02/2010 purchased 110,000 BIOTER's common registered shares of total value of Euro 16,500.00
2) the shareholder DESAN HOLDING SA, person obligated to notify pursuant to Law 3340/2005, on 06/02/2010 sold 205,490 BIOTER's common registered shares of total value of Euro 30,823.50