BIOTER S.A. pursuant to Law 3556/2007 announces that the shareholder Mr.George Mavroskotis General Manager and Managing Director of BIOTER SA, person obligated to notify pursuant to Law 3340/2005, 1) on 02/29/2008 purchased 7,050 BIOTER's common registered shares of total value of Euro 5,617.99 and 2) on 03/03/2008 purchased 7,000 BIOTER's common registered shares of total value of Euro 5,621.42