BIOTER S.A. pursuant to Law 3556/2007 announces that the shareholder Mr.George Mavroskotis General Manager and Managing Director of BIOTER SA, person obligated to notify pursuant to Law 3340/2005, on 12/21/2007 purchased 214,400 BIOTER's common registered shares of total value of Euro 214,400 and on 12/24/2007 purchased 24,000 BIOTER's common registered shares of total value of Euro 24,960.00