BIOTER S.A.

Announcement pursuant to Law 3556/2007

BIOTER S.A. pursuant to Law 3556/2007 announces that the shareholder Mr.George Mavroskotis General Manager and Managing Director of BIOTER SA, person obligated to notify pursuant to Law 3340/2005, on 12/17/2007 purchased 60,000 BIOTER's common registered shares of total value of Euro 58,353.75.