BIOTER S.A.

Announcement.

BIOTER S.A. pursuant to Law 3556/2007 announces that the shareholder Mr.George Mavroskotis General Manager and Managing Director of BIOTER SA, person obligated to notify pursuant to Law 3340/2005, on 12/12/2007 purchased 2,400 BIOTER's common registered shares of total value of Euro 2,358.94 and on 13/10/2007 purchased 12,700 BIOTER's common registered shares of total value of Euro 12,469.18